Browsing Experimentally Confirmed database

Result: Your query found 20 resistance gene(s) from the BacMet Experimentally Confirmed database

Gene_nameExperimentally Verified Resistance Gene InformationPredicted Resistance Gene Information
arsA
  • BacMet ID: BAC0030
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase; Determinants of a membrane-associated oxyanion-stimulated ATPase protein; energizes the arsenite efflux pump by ATP hydrolysis; Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

    		• Similar resistance genes in 'BacMet Predicted database'
    arsA
  • BacMet ID: BAC0571
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

    		• Similar resistance genes in 'BacMet Predicted database'
    arsA
  • BacMet ID: BAC0572
  • Code for: Enzyme
  • Family: ArsA ATPase family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Anion-transporting ATPase. Catalyzes the extrusion of the oxyanions arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents.
  • Length (amino acid): 583
  • Reference: Chen et al. 1986; Pubmed- 3021763

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0031
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773 (E. coli), Plasmid IncN R46 (E. coli), Plasmid R46 (Salmonella typhimurium)
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Arsenic pump membrane protein, located in cell inner membrane. Involved in arsenite and antimonite resistance. Thought to form a channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Tisa et al. 1990; Pubmed- 1688427, Chen et al. 1986; Pubmed- 3021763

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0574
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: Plasmid pI258
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Ji and Silver 1992; Pubmed- 1534328

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0575
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus xylosus
  • Location: Plasmid pSX267
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Rosenstein et al. 1992; Pubmed- 1534327

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0576
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Involved in arsenical resistance. Thought to form the channel of an arsenite pump.
  • Length (amino acid): 429
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0578
  • Code for: Efflux
  • Family: ArsB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Part of arsenic resistance operon of Acidiphilium multivorum AIU 301 plasmid pKW301.
  • Length (amino acid): 429
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

    		• Similar resistance genes in 'BacMet Predicted database'
    arsB
  • BacMet ID: BAC0579
  • Code for: Efflux
  • Family: ACR3 family.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Synechocystis sp. PCC 6803
  • Location: Chromosome
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Able to export both As(III) and Sb(III) and providies a example of convergent evolution between both families of arsenite transporters.
  • Length (amino acid): 383
  • Reference: Lopez-Maury et al. 2003; Pubmed- 12949088

    		• Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0582
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Tisa et al. 1990; Pubmed- 1688427, Chen et al. 1986; Pubmed- 3021763

    		• Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0583
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

    		• Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0584
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Acidiphilium multivorum (strain DSM 11245 / JCM 8867 / AIU301)
  • Location: Plasmid pKW301
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance
  • Length (amino acid): 141
  • Reference: Suzuki et al. 1998; Pubmed- 9464374

    		• Similar resistance genes in 'BacMet Predicted database'
    arsC
  • BacMet ID: BAC0585
  • Code for: Enzyme
  • Family: arsC family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Yersinia enterocolitica
  • Location: Plasmid pYV
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Reduction of arsenate [As(V)] to arsenite [As(III)]. This protein expands the substrate specificity of ArsAB pump which can extrude arsenite and antimonite to allow for arsenate pumping and resistance.
  • Length (amino acid): 141
  • Reference: Neyt et al. 1997; Pubmed- 9006011

    		• Similar resistance genes in 'BacMet Predicted database'
    arsD
  • BacMet ID: BAC0587
  • Code for: Regulator
  • Family: ArsD family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Arsenical resistance operon trans-acting repressor ArsD.
  • Length (amino acid): 120
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

    		• Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0589
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid R773
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Wu and Rosen 1991; Pubmed- 1838573

    		• Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0590
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus aureus
  • Location: Plasmid pI258
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 104
  • Reference: Ji and Silver 1992; Pubmed- 1534328

    		• Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0591
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli
  • Location: Plasmid IncN R46
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Bruhn et al. 1996; Pubmed- 8674982

    		• Similar resistance genes in 'BacMet Predicted database'
    arsR
  • BacMet ID: BAC0592
  • Code for: Regulator
  • Family: Contains 1 HTH arsR-type DNA-binding domain.
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Staphylococcus xylosus
  • Location: Plasmid pSX267
  • Compound: Arsenic (As), Antimony (Sb), Bismuth (Bi)
  • Description: Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)).
  • Length (amino acid): 117
  • Reference: Rosenstein et al. 1992; Pubmed- 1534327

    		• Similar resistance genes in 'BacMet Predicted database'
    glpF
  • BacMet ID: BAC0181
  • Code for: Channel
  • Family: Major Intrinsic protein (MIP) superfamily. MIP/aquaporin family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Escherichia coli (strain K12)
  • Location: Chromosome
  • Compound: Antimony (Sb), Arsenic (As), Glycerol [class: Alcohol]
  • Description: Glycerol uptake facilitator protein GlpF; Transporter of glycerol across the cytoplasmic membrane, with limited permeability to water and small uncharged compounds such as polyols
  • Length (amino acid): 281
  • Reference: Sanders et al. 1997; Pubmed- 9150238, Meng et al. 2004; Pubmed- 14970228

    		• Similar resistance genes in 'BacMet Predicted database'
    pgpA/ltpgpA
  • BacMet ID: BAC0311
  • Code for: Enzyme
  • Family: ABC transporter superfamily. ABCB family
  • Sequence: FASTA
  • Cross-database IDs: Link
  • Organism: Leishmania tarentolae (Sauroleishmania tarentolae)
  • Location: Chromosome
  • Compound: Arsenic (As), Antimony (Sb)
  • Description: Multidrug resistance protein PgpA
  • Length (amino acid): 1548
  • Reference: Papadopoulou et al. 1994; Pubmed- 7909316, Callahan et al. 1994; Pubmed- 7891738

    		• Similar resistance genes in 'BacMet Predicted database'
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